Overview Intravesical chemotherapy is a treatment for bladder cancer. The American Cancer Society describes intravesical chemotherapy as chemotherapy that is placed directly into the bladder through a catheter, instead of given orally or intravenously. There are side effects with this kind of chemotherapy, as with any cancer treatment, but not everyone will experience every side effect, and they are typically manageable and tend to resolve once treatment has ended.
Side effects of intravesical chemotherapy depend on which drugs are being given. BCG side effects can include flu-like symptoms such as fever or chills, fatigue, pain with urination, urinary frequency and blood in the urine, according to chemocare.com. Side effects of interferon listed by the American Cancer Society are typically flu-like symptoms, bone pain, headaches, nausea, vomiting and trouble concentrating. Side effects of other cancer drugs during intravesical chemotherapy typically involve a burning feeling in the bladder, irritation with urination and fatigue.
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